Secondary Ion Mass Spectrometry on the Helium Ion Microscope: methodologies for analysis of nanomaterials
نویسندگان
چکیده
منابع مشابه
Quantitative Secondary Ion Mass Spectrometry
mental standards, and by statistical and systematic errors in the measurement of x-ray lines and in the separation of line intensity from spectral background. The errors in estimating the characteristics of the detector system, with exception of deadtime effects, cancel when the emission from the specimen is divided by that from the standard. The estimate of achievable accuracy of EPMA and the ...
متن کاملLiquid Secondary Ion Mass Spectrometry
Liquid secondary-ion mass spectrometry (liquid SIMS) is an obsolescent ionization technique that revolutionized the analyses of large biological molecules in the 1980s. The term includes fast atom bombardment mass spectrometry (FAB-MS). The technique has been largely superseded by electrospray ionization. This account will cover the history of the technique, the principles of the operation, and...
متن کاملSecondary Electron Imaging in the Helium Ion Microscope
Secondary electrons (SE) have been for many years the most user friendly, versatile, and convenient modes of imaging in the scanning electron microscope. The Helium Ion Microscope (HIM) also generates secondary electrons (iSE) and potentially offers significant advantages compared to the conventional SEM including much enhanced spatial resolution and improved image contrast. There are, however,...
متن کاملSecondary Ion Mass Spectrometry of Proteins
The adsorption of bovine serum albumin (BSA), immunoglobulin G (IgG) and fibrinogen (Fgn) on fluorinated selfassembled monolayers have been studied using time of flight secondary ion mass spectrometry (ToF-SIMS) and Spectroscopic Ellipsometry (SE). The objective of the work has to establish the utility of ToF-SIMS for the determination of the amount of protein adsorbed on the surface. Quantific...
متن کاملCellular imaging with secondary ion mass spectrometry.
This article is a concise review of the application of secondary ion mass spectrometry (SIMS) to the imaging of biological cells. The paper covers the various advantages and disadvantages of different approaches to SIMS analysis with respect to the information that can be gained from the interrogation of the cells. Current successes, pitfalls and future potential for SIMS in cell imaging are di...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Microscopy and Microanalysis
سال: 2018
ISSN: 1431-9276,1435-8115
DOI: 10.1017/s1431927618005573